Old Fashioned Love

https://digitalcommons.library.umaine.edu/mmb-vp/4020/thumbnail.jp

Open Your Heart

https://digitalcommons.library.umaine.edu/mmb-vp/3343/thumbnail.jp

Two Decades of Investment in Substance-Use Prevention and Treatment

This FSG report assesses two decades of investment by the Robert Wood Johnson Foundation (RWJF) to reduce harm from alcohol and other drugs in the United States. Over this time, the foundation spent nearly $700 million in pursuit of this goal, representing the largest investment in substance use prevention and treatment ever made by a nonprofit, philanthropic funder.This retrospective assessment explores the evolution of the foundation's substance-use strategies and goals, examines what RWJF achieved as a result of these efforts, and identifies strengths and challenges of the foundation's approach

Advances in quantum machine learning

Here we discuss advances in the field of quantum machine learning. The following document offers a hybrid discussion; both reviewing the field as it is currently, and suggesting directions for further research. We include both algorithms and experimental implementations in the discussion. The field's outlook is generally positive, showing significant promise. However, we believe there are appreciable hurdles to overcome before one can claim that it is a primary application of quantum computation.Comment: 38 pages, 17 Figure

Etiology of nocturia response in men with diminished bladder capacity

Aims: To test the hypothesis that patients with nocturia owing to diminished global or nocturnal bladder capacity improve via increased bladder capacity. Methods: This is a retrospective analysis of voiding diaries completed at a VA urology clinic between 2008-2017. Inclusion required patients aged at least 18 years, male, undergoing treatment for nocturia, and having completed at least two 24-hour voiding diaries >= 1 month apart. Patients were divided into two cohorts: responders (any decline in nocturia) and non-responders (no change or any increase in nocturia). Patients were further sub-stratified as having low global bladder capacity (maximum voided volume [MVV] = 200 mL). Wilcoxon rank-sum was applied with a Bonferroni correction to test significance. Results: Forty pre- and post-treatment diaries from 27 patients, and 19 pre- and post-treatment diaries from 17 patients were identified as having low global and low nocturnal bladder capacity, respectively. Nocturia responders with low global bladder capacity demonstrated significant decline compared to non-responders in nocturnal urine volume (NUV) (-140 vs +75, P < 0.01) and nocturnal bladder capacity index (NBCi) (-0.59 vs +0.23, P < 0.01). Patients with low nocturnal bladder capacity similarly demonstrated decreased NUV (-30 vs +160, P = 0.04) and NBCi (-1.4 vs +0.33, P < 0.01). There was no significant change in MVV or NMVV for either group. Conclusions: Treatment directed at lowering nocturnal urine production and enabling patients to consistently void at capacity is a rational strategy to treat nocturia in patients with low bladder capacity

Noncompact Lattice Simulations of SU(2) Gauge Theory

Wilson loops have been measured at strong coupling, $\beta=0.5$, on a $12^4$ lattice in noncompact simulations of pure SU(2) without gauge fixing. There is no sign of quark confinement.Comment: 4 pages, UNM-93-nl